The goal of this case control study is to detect serum isthmin-1 level in RA patient compered to healthy control . The main questions it aims to answer are:
what is the serum isthmin-1 level in RA patient? what is the correlation between serum isthmin-1 and RA disease activity? what is the correlation between serum isthmin-1 level and MSUS finding in RA patients?
None
Patients less than 18 years old.
Patients with other autoimmune diseases.
Participants with active infections, malignancies or diabetes.
Recent hand surgery, trauma, deformity and neurological conditions affecting hand function
Adult patients (≥18 years old) clinically diagnosed with rheumatoid arthritis according to the 2010 ACR/EULAR classification criteria.
Case-control
Prospective
Not listed
Detection of serum isthmin-1 level in RA patients compared to healthy controls.
The quantitative level of Human ISM1 will be measured with a commercial enzyme-linked immunosorbent assay(ELISA) kit.
To correlate serum ISM1 levels with disease activity in RA
through clinical and acute phase reactant
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Amera Imam Abdel - Ghany Ahmed
Lead sponsor
Assiut University
Sponsor institution
This trial is not recruiting at the moment. You can still explore other options:
