Kimel Family Centre for Brain Health and Wellness
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorBaycrest
About this trial
Participants (n=450; aged 50+; without a diagnosis of dementia; sufficiently fluent in English to complete the assessments and engage in programming) receive a comprehensive dementia risk assessment, including nonmodifiable and modifiable risk factors, from which they receive a Personalized Dementia Risk Report and Program Strategy, indicating their health conditions increasing and their risk level in five modifiable risk domains: physical activity, brain- healthy eating, cognitive engagement, social connections, and mental wellbeing. Equipped with this information, participants enroll in programs within the Centre to address their risk factors. Changes to their dementia risk, cognition, and Personalized Program Strategy are communicated through re-assessments of risk factors every six months (risk and cognition) and every year (comprehensive assessment).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged 50 years or older
Sufficiently fluent in English to complete the assessments and participate in programming.
Disqualifiers
Diagnosis of dementia.
Trial design
Design model
Single group
Treatments tested in this trial
Physical Activity
BehavioralParticipants can chose (with input from a kinesiologist as required) from courses of varying intensity in our gym, warm water pool, or classrooms.
Brain-healthy Eating
BehavioralParticipants take five foundational courses: Brain-healthy eating, Healthy protein choices, Colour your diet: Maximize the benefits of fruits and vegetables; Interpreting nutrition facts labels; and Salt and sugar: How much is too much? They are also encouraged to take additional nutrition programs.
Cognitive Engagement
BehavioralParticipants can sign up for any lecture, discussion group, book club, creative arts program, etc. linked to the Cognitive Engagement risk factor.
Social Connections
BehavioralSocial Connections are baked into all other programming. Our instructors are trained in how to foster connections among participants, through peer coaching, ice-breakers, etc., and are asked to leave some time at the beginning and end of programs for participants to chat. We also hold special social events such as game nights.
Mental Wellbeing
BehavioralParticipants are encouraged to enroll in one a week of relevant programming (e.g., meditation, relaxation).
Treatment groups
450 Participants
are divided into 5 treatment groupsGroup A: Physical ActivityActive comparator 1 intervention
Group B: Brain-healthy EatingActive comparator 1 intervention
Group C: Cognitive EngagementActive comparator 1 intervention
Group D: Social ConnectionsActive comparator 1 intervention
Group E: Mental WellbeingActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Physical Activity
Hours of moderate-to-vigorous physical activity a week, as determined by the CHAMPS (0 - 168, with higher scores indicating greater activity).
Time frame
Every six months over two years.2
Cognition
We expect cognition to be maintained or improved, as assessed by Cogniciti's Brain Health Assessment, to the extent that participants adhere to their Personalized Program Strategy.
Time frame
We expect to see this at the two year mark.3
Brain-Healthy Eating
Brain-healthy eating as assessed by the Brain Health Food Guide derived Eating Pattern Self-Assessment (range 0 - 15, with higher scores indicating greater adherence to the Brain Health Food Guide).
Time frame
Every six months over two years.4
Cognitive Engagement
Amount of engagement in higher-order cognitively engaging activities, as assessed by the Higher Cognition subscale of the Florida Cognitive Activities Scale (range 0-40, with higher scores indicated greater engagement).
Time frame
Every six months over two years. Source ClinicalTrials.gov