Health TrialsbyHealthPanel

Kinematic vs Mechanical Alignment in High Tibial Osteotomy

ConditionsOsteo Arthritis of the KneeGenu Varum
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorAssiut University

About this trial

To compare between kinematic and mechanichal alignment after High Tibial Osteotomy (clinically and radiologically)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Clinical: 1. Age : Adult with symptomatic osteoarthritic varus knee 2-Medial knee pain with functional limitation ≥6 months despite optimized non-operative care.

Disqualifiers

1- Predominantly lateral compartment OA 2- severe patellofemoral arthritis 3- Prior high tibial osteotomy, knee arthroplasty, or complex fracture around the knee 4-Inflammatory arthropathies (eg, rheumatoid arthritis) 5- end stage medial compartment osteoarthritis with bone erosions 6-chondrocalcinosis

Trial design

Design model

Parallel

Treatments tested in this trial

  • high tibial osteotomy

    Procedure/Surgery

    High tibial osteotomy (HTO) is a well-established joint-preserving procedure for younger and active patients with medial compartment osteoarthritis associated with varus malalignment. By laterally shifting the mechanical axis of the lower limb, HTO unloads the diseased medial compartment, alleviates pain, and delays the need for knee arthroplasty

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: group 1 (mechanical alignment)Other 1 intervention
Group B: group 2 (kinematic alignment)Other 1 intervention

Trial outcomes

Primary outcomes

1

oxford knee score

a validated, patient-reported outcome measure specifically designed for knee pathology. The OKS is a short, patient-centred questionnaire that assesses both pain and functional ability from the patient's perspective. It is widely recognized for its simplicity, reliability, and sensitivity to clinically meaningful changes following knee surgery. By adopting a PROM as the main clinical outcome, this study emphasizes patient-relevant benefit rather than relying solely on radiographic or surrogate measures. The OKS will be assessed preoperatively and at scheduled postoperative follow-up intervals, with the 12-month endpoint defined as the primary time point.

Time frame
12 months

Secondary outcomes

1

Knee Injury and Osteoarthritis Outcome Score (KOOS)

Time frame
12 months
2

University of California Los Angeles (UCLA) Activity Score

Time frame
12 months

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

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