ConditionsCardiac Arrest (CA)Intensive Care Unit (ICU) AdmissionReturn of Spontaneous CirculationComatose
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssistance Publique - Hôpitaux de Paris
About this trial
The purpose of this study is to assess the prognostic value of absolute value and kinetic of neurofilament light chain (NFL) collected at different time points (at admission, 12h, 24h, 48h, 72h, 96h, and day 7 after ICU admission) in predicting poor and good neurological outcome in comatose patients after cardiac arrest.
Eligibility criteria
Qualifiers
Patients admitted to the ICU for cardiac arrest,
Patients who regained consciousness following in-hospital or out-of-hospital cardiac arrest,
Patients in a coma upon arrival in the ICU, defined by a Glasgow Coma Scale (GCS) score <8,
Patients included in the AfterROSC2 cohort,
Disqualifiers
Terminally ill patients (death expected within 3 hours of admission to the ICU),
Minors,
Patients under legal guardianship,
Pregnant women,
Trial design
Treatments tested in this trial
- Value of neurofilament light chain (NFL) at different time points
Treatment groups
270 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov