About this trial
We propose to analyze the kinetics of the main marker of inflammation in GCA in order to understand its links with initial clinical manifestations and the possible appearance of complications and/or relapses.
Early assessment of the rate of CRP normalization would enable us to adapt the therapeutic strategy in order to avoid complications and/or relapses.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients aged 18 or older hospitalized in the internal medicine department with a new diagnosis of ACG
Personne affiliée ou bénéficiaire d'un régime de sécurité sociale
Free and informed consent signed by the participant and the investigator
Disqualifiers
Patients scheduled to be placed on a sparing regimen during hospitalization
Patients with renal insufficiency (eGFR ≤ 60 mL/min/1.73 m²)
Patients with a history of corticosteroid-treated pseudopolyarthritis
Patients with ACG and visual impairment (severity criterion)
Trial design
Single group
Treatments tested in this trial
Blood tests to measure CRP
Diagnostic testBlood tests to measure CRP levels
Treatment groups
Trial outcomes
Primary outcomes
CRP testing
1. Immediately before starting corticosteroids 2. Every day immediately before taking the morning dose of corticosteroids, for 5 days, and up to 7 days if levels do not return to normal 3. Then once a week for up to 1 month after starting corticosteroids 4. Then monthly for 8 months during follow-up visits 5. Then every 2 months for up to 1 year
Secondary outcomes
Determining Corticosteroid Dosages and Estimating Their Half-Lives
Corticosteroid Dosage: Take daily, just before your morning dose of corticosteroids
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: