LA Function and Dimensions As Predictors of Disease Activity in RA

Trial design

Treatments tested in this trial

• echocardography

  Device DeviceA medical device, or sometimes a sham device used for comparison, that is being studied.

  Patients will be subjected to transthoracic echocardiography including, the following parameters will be measured: * Left ventricular (LV) dimensions: end diastolic and systolic dimensions and LV ejection fraction (EF). * Trans- mitral Doppler flow velocities including early (E) and late(A) diastolic velocities, E/A ratio. * LA anteroposterior diameter measure from 2D parasternal long axis view targeted M-mode. * LA superior-inferior and medio-lateral diameters measure from the apical 4 chamber view. * LA volume included: * Maximal LA volume measure at the end of systole * Minimal LA volume will be measured at end diastole just at the closure of the mitral valve. * Pre contractile LA volume ( LAV pre-A\] measured at P-wave onset on ECG just before atrial contraction.

  Show more

• musculoskeletal ultrasonography

  Device DeviceA medical device, or sometimes a sham device used for comparison, that is being studied.

  Ultrasound detected synovitis t

• lipid profile test

  Diagnostic test Diagnostic testA test used to detect or assess a condition, such as imaging or a laboratory test.

  The lipid profile typically includes measurement of total cholesterol, HDL-cholesterol (often called good cholesterol), LDL-cholesterol (often called bad cholesterol), and triglycerides.

• C reactive protein

  Diagnostic test Diagnostic testA test used to detect or assess a condition, such as imaging or a laboratory test.

  A c-reactive protein test measures the level of c-reactive protein (CRP) in a sample of your blood. CRP is a protein that your liver makes. Normally, you have low levels of c-reactive protein in your blood. Your liver releases more CRP into your bloodstream if you have inflammation in your body. High levels of CRP may mean you have a serious health condition that causes inflammation.

  Show more

• Complete blood count CBC

  Diagnostic test Diagnostic testA test used to detect or assess a condition, such as imaging or a laboratory test.

  A complete blood count, or CBC, is a blood test that measures many different parts and features of your blood, including: Red blood cells, which carry oxygen from your lungs to the rest of your body. White blood cells, which fight infections and other diseases. There are five major types of white blood cells. A CBC test measures the total number of white cells in your blood. A different test called a CBC with differential measures the number of each type of these white blood cells. Platelets, which stop bleeding by helping your blood to clot. Hemoglobin, a protein in red blood cells that carries oxygen from your lungs to the rest of your body. Hematocrit, a measurement of how much of your blood is made up of red blood cells. Mean corpuscular volume (MCV), a measure of the average size of your red blood cells.

  Show more

• Erythrocyte sedimentation rate (ESR).

  Diagnostic test Diagnostic testA test used to detect or assess a condition, such as imaging or a laboratory test.

  An erythrocyte sedimentation rate (ESR) is a blood test that that can show if you have inflammation in your body. Inflammation is your immune system\'s response to injury, infection, and many types of conditions, including immune system disorders, certain cancers, and blood disorders.

  Show more

• x ray of the hand

  Device DeviceA medical device, or sometimes a sham device used for comparison, that is being studied.

  The X-ray may show a hand with advanced rheumatoid arthritis. \"Bone erosion\" means cartilage and bone are worn away. \"Bone displacement\" means that a bone has moved out of its normal position. This X-ray shows how bone erosion and bone displacement can change the shape of the hand.

  Show more