Health TrialsbyHealthPanel

Laboratory Heat Biomarker and Cooling Interventions

ConditionHyperthermia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorStanford University

About this trial

Our study has two goals. The first goal is to find a blood test that can detect signs of strain from heat in the body ("a biomarker"). Second, the study team wants to identify types of devices that can help people cool down quickly.

By identifying biomarkers for heat strain, scientists can better track and treat the health effects of heat. The study team will identify such biomarkers by simulating, in a laboratory-based environment, the heat and physical work that real-world workers experience.

In addition, the study team plans to test two cooling technologies that might keep people cool during physical activity.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 18-50

Able to communicate in English or Spanish

General good health

A lifestyle that includes regular patterns of modest exercise

Disqualifiers

Cannot provide informed consent

Known history of cardiac arrhythmias or having a pacemaker

Difficulty swallowing pills

Planned upcoming X-ray tests or MRI

Trial design

Design model

Crossover

Treatments tested in this trial

  • Hand cooling table

    Other intervention

    A participant can rest their hand on the cooling table after the one hour exercise session, and this should cool their body quickly. Cold water is pumped throughout the cooling table.

  • Cooling bandana

    Other intervention

    A participant will tie a bandana that has been soaked in cold water onto their forehead. They will wear this bandana during the one hour exercise session.

Treatment groups

30 Participants
are divided into 6 treatment groups

6

Treatment groups

See each treatment group below.

Group A: Biomarker testing (A), Cooling bandana (B), Hand cooling table (C)Experimental treatment 2 interventions
Group B: Biomarker testing (A), Hand cooling table (C), Cooling bandana (B)Experimental treatment 2 interventions
Group C: Cooling bandana (B), Biomarker testing (A), Hand cooling table (C)Experimental treatment 2 interventions
Group D: Cooling bandana (B), Hand cooling table (C), Biomarker testing (A)Experimental treatment 2 interventions
Group E: Hand cooling table (C), Biomarker testing (A), Cooling bandana (B)Experimental treatment 2 interventions
Group F: Hand cooling table (C), Cooling bandana (B), Biomarker testing (A)Experimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

Core body temperature

Time frame
Baseline through end of study (approximately 2 months).

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Stanford University

Lead sponsor

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: