Large Language Model for Understanding and Monitoring Elderly Neurocognition

ConditionDementia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorNorthumbria Healthcare NHS Foundation Trust

About this trial

Dementia affects millions of people worldwide, and early diagnosis is essential for getting the right care and support. Doctors rely on collateral histories (accounts from family members or caregivers) to understand changes in a person's memory and thinking. However, these histories can be incomplete, unstructured, or difficult to obtain, making diagnosis more challenging.

This study will test LUMEN (Large Language Model for Understanding and Monitoring Elderly Neurocognition), an AI-powered conversation tool designed to help caregivers describe their loved one's symptoms more effectively. By asking structured questions and guiding the conversation, LUMEN can create clear, well-organised reports for memory clinic doctors. This could make assessments quicker, more accurate, and less stressful for families.

We will test LUMEN in real-world clinics by asking caregivers and doctors to use it and provide feedback. We want to understand how easy it is to use, whether it could improve the quality of information shared, and how it fits into existing NHS memory clinic processes. We will also run co-production workshops with community groups to ensure the tool is accessible to people from diverse cultural and language backgrounds.

This research is exciting because it explores how artificial intelligence can improve dementia care. If successful, LUMEN could enhance the diagnostic process, reduce carer burden, and help more people access dementia support sooner. In the future, this tool could be used nationwide in memory clinics, improving care for thousands of families.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Patient and carer dyads: patients attending the Memory Clinic for assessment of cognitive problems. Clinicians: specialist doctors or advanced nurse practitioners responsible for dementia diagnosis

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • LUMEN prototype software interaction

    Other intervention

    This is a prototype software which seeks to gather collateral information relevant to a dementia clinical assessment.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Patient-carer dyads1 intervention
Group B: Clinicians1 intervention

Trial outcomes

Primary outcomes

1

SUS (System Usability Scale)

10-item Likert-scale questionnaire assessing ease of use (score ≥70 = good usability).

Time frame
Immediately after use of software
2

NASA-TLX (Task Load Index):

Evaluates perceived cognitive workload (scores 0-29 = low workload).

Time frame
Immediately after prototype interaction

Secondary outcomes

Other outcomes

1

Thematic analysis

Qualitative analysis of dialogues from semi-structured interviews

Time frame
1-10 days after use of prototype software

Sponsors and contacts

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