Laser-based Photoacoustic Tomography of Human Inflammatory Arthritis

ConditionArthritis, Rheumatoid

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorUniversity of Michigan

About this trial

The purpose of this feasibility study is to determine if a new emerging technology called photoacoustic tomography (PAT) can be adapted for use in humans for the detection of chronic rheumatoid arthritis.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Men and women 18 years of age or older can participate in this study.

Patients can participate in this study if they have had rheumatoid arthritis for more than 2 years and their rheumatologist has referred them to this study.

Patients can participate as a healthy volunteer with a known history of rheumatoid arthritis.

Disqualifiers

Patients, who have electrically, magnetically or mechanically activated implants such as heart pacemaker, magnetic surgical clips, prostheses or implanted neurological stimulator.

Pregnant patients.

Patients who is claustrophobic.

Patients with impaired renal function cannot participate in this study such as elevate creatinine clearance, patients on kidney dialysis etc.

Trial population

Subjects are 1) people who are either healthy volunteers or have patients who have rheumatoid arthritis for more than 2 years and who have a rheumatologist who referred them to this study.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Laser Based Photoacoustic Tomography, MRI, Ultrasound
Procedure/Surgery
Healthy subjects will have scans on finger joints with any of the scanning methods described above.
laser based photoacoustic tomography, MRI, ultrasound
Procedure/Surgery
Subjects with arthritis will have scans on finger joints with any of the scanning methods described above.

Treatment groups

113 Participants

are divided into 2 treatment groups

Group A: Rheumatoid Arthritis1 intervention

Group B: Normal controls1 intervention

Trial outcomes

Primary outcomes

Photoacoustic Imaging

To determine if photoacoustic imaging (PAT) can accurately assist in the diagnosis of chronic rheumatoid arthritis, with data collected every 2 weeks for a maximum of 10 weeks.

Time frame

10 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Michigan

Lead sponsor

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborator

Source ClinicalTrials.gov

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