About this trial
Cerebral palsy (CP) is characterized by a fixed lesion that affects the neurological system during development. Pathologic hip conditions, such as subluxation or dislocation, are of great concern in non-ambulatory CP patients. Complete hip dislocations are commonly encountered in non-ambulatory CP patients and this can be quite problematic if pain is experienced or when sitting, balance, posture, or hygiene become affected.
The management of this patient population includes both reconstructive surgery, which aimed to center the dislocated femoral head into the acetabulum, and salvage surgeries, which are performed to reduce associated pain and/or functional deficits (e.g., sitting problems).
There are many options for salvage management of dislocated hips in CP patients, including proximal femoral resection (PFR) either with or without cartilage capping, proximal femoral valgus osteotomy, hip arthrodesis, and prosthetic hip arthroplasty.
To date, there is no conclusive evidence to determine which option is superior compared to the others in terms of efficacy and postoperative complications in CP patients due to the lack of a comparison group and the small number of included patients. Furthermore, the decision to take reconstructive vs. salvage procedures is still a matter of debate in the literature.
Therefore, this study is being conducted to compare outcomes between PFR, reconstructive hip surgery, and proximal femur valgus osteotomy in terms of clinical improvement (Including pain) and complications
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Lesion: neglected deformed dislocated hip (Deformed head Group B, C, and D according to Rutz classification modified from MCPHCS )
Non-ambulatory: as defined by GMFCS level IV and V
Disqualifiers
Ambulatory patients
patients underwent any previous hip bony procedures.
Non-deformed Femoral head Group A according to Rutz classification
Neuromuscular hip dislocation other than cp.
Trial design
Parallel
Treatments tested in this trial
Hip reconstruction surgery.
Procedure/SurgeryThis group will undergo Hip reconstruction surgery Anterior approach overlying the iliac crest: open reduction, pelvic osteotomy and pelvic osteotomy. Lateral approach: derotation-varization osteotomy and shortening of femur, internal fixation
Proximal femoral resection
Procedure/SurgeryResection of the proximal part of the femur below the level of the lesser trochanter by 2 to 3 cm and constructed a capsular flap across the acetabulum. The quadriceps muscle will be sutured around the resected end of the femur
Proximal femoral valgus ostetomy
Procedure/SurgeryThe patient is positioned in the lateral decubitus Position A straight incision is cantered over the greater trochanter and extends proximally. Head and neck are resected. A closing wedge, shortening, valgus-producing osteotomy of 40 to 50 degrees is marked just below the lesser trochanter and fixed by a plate
Treatment groups
Trial outcomes
Primary outcomes
Radiological changes
Plain radiograph x-ray is used to assess the Migration percentage
Radiological changes
Plain radiograph x-ray is used to assess Pelvic obliquity
Radiological changes
Plain radiograph x-ray is used to asses Acetabular index.
Radiological changes
Plain radiograph x-ray is used to assess Femoral head sphericity
Sponsors and contacts
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Muhammad Ayoub
Lead sponsor
Ain Shams University
Sponsor institution