Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age18-99
SponsorIndiana University

About this trial

Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant

Eligibility criteria

Qualifiers

Patients >18 years of age

Patients will be recruited only if cancer-free at clinical evaluation time.

For the cases a confirmed TC diagnosis who received one or more cycles of CBCT-based chemotherapies (CBCT group, Arm 2)

For the cases with a confirmed TC diagnosis who received one or more cycles of CBCT-based chemotherapies and underwent BMT for relapsed refractory disease (CBCT & BMT group, Arm 3).

Disqualifiers

Prior known myocardial infarction (MI), atherosclerotic cardiovascular disease (ASCVD)

Significant renal disease (GFR<40)

Allergy to iodinated contrast

Antecedent chemotherapy for another primary cancer.

Trial design

Treatments tested in this trial

  • Lipid profile
  • Coronary artery assessment
  • Hormone levels for hypogonadism

Treatment groups

150 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Indiana University

Lead sponsor

National Institutes of Health (NIH)

Collaborator

JDS Foundation Testis Cancer Clinical Trials Support Fund

Collaborator