" The French Gut " is a national contribution aiming to collect 100,000 faecal samples and associated nutritional and clinical data by 2027. Le French Gut is initiated by MetaGenoPolis-INRAE, supported by INRAE with Prof. R. Benamouzig, (AP-HP) as principal investigator of the project. The main goal of this national trial is a better understanding of the observed heterogeneity between gut microbiome of healthy subjects, its connections with the diet and lifestyle, but also changes in gut microbiota associated with diseases (diabetes, obesity, allergies, cancer, Parkinson, Alzheimer…).
Persons over the age of 18 living in France.
Consent form signed electronically.
Non-adult person (declarative);
Person not living in France (declarative);
None
General population residing in France
Cohort
Other
Not listed
Characterize the heterogeneity and diversity of the gut microbiota of subjects living in France
The gut microbiota of participants will be characterized by describing the presence and abundance in the samples of each gut microbial genes listed in our up-to-date gene catalogue. From these data, the presence and abundance of the different taxonomic ranks will be deduced, ranging from a fine granularity at species and strain level to a more 'zoomed out' phylum level. The richness and diversity of the microbiome (genes and species) will be described. The functional modules, corresponding to the metabolic pathways encoded by the species detected in each sample, will be determined.
Study the variations in the gut microbiota as a function of microbial profile
Study the variations in the gut microbiota as a function of age
Study the variations in the gut microbiota as a function of socio-demographic and anthropometric characteristics
Richness and diversity of the microbiota (genes and species);
Study the variations in the gut microbiota as a function of lifestyle and eating habits
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Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Lead sponsor
Assistance Publique - Hôpitaux de Paris
Collaborator
