Leucine Requirements in School-Age Children

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-10
SponsorUniversity of British Columbia

About this trial

Leucine is an essential amino acid, which serves a special purpose of signaling cell growth in muscle in addition to making up protein. Essential amino acids like leucine need to be eaten every day from our foods like meat, dairy, eggs, beans, and nuts, as they cannot be made by our bodies. The current recommendation for leucine in the diet of school-age children are based upon adult needs. This study will measure the leucine requirement in children aged 6-10 years old using an non-invasive technique with special diets, safe stable isotopes, and simple breath collections. Creating guidelines based on measured requirements for leucine in this age group is essential for supporting optimal growth in healthy children.

Eligibility criteria

Qualifiers

Healthy children

Aged 6 to 10 years at enrollment

Body weight between the 3rd and 85th percentile according to WHO Child Growth Standards

Assent from the child and written informed consent from parent(s) and/or legal guardian(s)

Disqualifiers

Diagnosis of any acute or chronic medical condition

Current use of prescription medication that may affect protein or energy metabolism

Recent weight loss

Recent illness (fever, vomiting, severe runny nose within the past 5 days)

Trial design

Treatments tested in this trial

  • Leucine Intake

Treatment groups

7 Participants
are divided into 1 treatment group

Sponsors and collaborators