LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorGeorge Mason University

About this trial

LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being. This study will develop and evaluate an enhanced multilingual LBM app for community-dwelling, diverse older adults with mild cognitive impairment (MCI) or at risk of MCI and their informal caregivers, including Hispanic/Latino, Asian American (as one of subgroups, Korean), Black or African American, and non-Hispanic White populations. The app provides culturally tailored life story prompts with audio and visual cues to encourage reminiscence and storytelling. The intervention aims to improve quality of life, reduce depressive symptoms and loneliness, and strengthen caregiver-care recipient relationships, with the potential to provide an accessible, non-pharmacological approach to supporting cognitive and emotional well-being.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Self-identified as Hispanic/Latino, Korean, Black/African American, and Non-Hispanic White

Speak and read Spanish, Korean, or English

Aged 60 years and older, with Montreal Cognitive Assessment (MoCA) test scores ranging 18-30 (with MCI: 18-25, or at risk for MCI: 26-30)

Have a local or in-home informal caregiver who can participate who is age 18 or older

Trial design

Design model

Parallel

Treatments tested in this trial

  • LifeBio Memory (LBM) digital reminiscence intervention

    Other intervention

    LifeBioMEMORY (LBM) is a multilingual digital reminiscence therapy platform that guides older adults through life story sharing using culturally relevant prompts, photos, and voice recording in Spanish, Korean, or English. The app includes "My Story" and "Fun Things to Do" features to support reminiscence and engagement while capturing personal narratives. Using machine learning, LBM generates personalized Life Story Books and summaries in the preferred language of the older adult and informal caregiver, with electronic and printed copies available. The intervention is designed to promote social engagement, strengthen caregiver relationships, and support person-centered care.

Treatment groups

168 Participants
are divided into 2 treatment groups
Group A: LifeBio Memory (LBM) digital reminiscence interventionExperimental treatment 1 intervention
Group B: Waitlist Control (Delayed LBM digital reminiscence intervention)Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

Primary Outcome

Health-Related Quality of Life (SF-12 Physical and Mental Component Summary Scores)

Time frame
Assessments will be conducted at baseline, 6 weeks, and 10 weeks.

Secondary outcomes

1

Center for Epidemiologic Studies Depression Scale (CES-D)

The Center for Epidemiologic Studies Depression Scale (CES-D) measures depressive symptoms. Total scores range from 0 to 60, with higher scores indicating greater depressive symptoms (worse outcome).

Time frame
Assessments will be conducted at baseline, 6 weeks, and 10 weeks.
2

Relationship Closeness Scale (RCS)

The Relationship Closeness Scale (RCS) measures perceived emotional closeness and relationship quality between the caregiver and care recipient. Total scores range from 6 to 24, with higher scores indicating greater relationship closeness (better outcome).

Time frame
Assessments will be conducted at baseline, 6 weeks, and 10 weeks.
3

UCLA Loneliness Scale

The 3-Item UCLA Loneliness Scale (UCLA-LS-3) measures perceived loneliness and social isolation. Total scores range from 3 to 9, with higher scores indicating greater loneliness (worse outcome).Time Frame: Assessments will be conducted at baseline, 6 weeks, and 10 weeks.

Time frame
Assessments will be conducted at baseline, 6 weeks, and 10 weeks.

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

George Mason University

Lead sponsor

National Institute on Aging (NIA)

Collaborator

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