Health TrialsbyHealthPanel

Link Between ASCorbemia Level and Osteoporosis

ConditionsOsteoporosisVitamin C DeficiencyVertebral Fractures
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age50+
SponsorCentre Hospitalier Universitaire de Nice

About this trial

This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis. Forty participants will be enrolled at the Rheumatology

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Men aged 50 yars or older ;

Postmenopausal women ;

Afilliated with a health insurance and system ;

Written informed consent obtained.

Disqualifiers

Legal protection measure (guardianship, curatorship);

inability to provide informed consent ;

refusal to participate ;

Vertebral fracture related to tumor,

Trial design

Design model

Parallel

Treatments tested in this trial

  • Plasma vitamin C assessment

    Diagnostic test

    Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient of the study

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: Osteoporosis with vertebral fractureExperimental treatment 1 intervention
Group B: Non-severe osteoporosisExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Plasma vitamin C concentration

Comparison of plasma vitamin C concentration (ascorbemia, µmol/L) between patients with osteoporotic vertebral fractures and patients with osteoporosis without vertebral fracture.

Time frame
day 1

Secondary outcomes

1

Association between plasma vitamin C level and number of vertebral fractures

Assessment of the relationship between plasma vitamin C concentration and the number of osteoporotic vertebral fractures

Time frame
day 1
2

Association between plasma vitamin C level and lumbar bone mineral density

Assessment of the relationship between plasma vitamin C concentration and lumbar spine bone mineral density measured by DXA.

Time frame
day 1

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Centre Hospitalier Universitaire de Nice

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: