Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
ConditionColorectal Cancer Metastatic
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Rochester
About this trial
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 18
Non-amenable to curative hepatic resection as defined by FLR <30%
Histologically confirmed adenocarcinoma of the colon or rectum
Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program
Disqualifiers
Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis.
Unwilling to consent
Trial population
Potential subjects for this registry must have Stage IV colorectal cancer with liver metastases and be candidates for liver transplantation based on multidisciplinary discussion by a tumor board.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Liver transplantation
Procedure/Surgeryliving donor liver transplantation
Treatment groups
25 Participants
are divided into 1 treatment groupGroup A: All Participants1 intervention
Trial outcomes
Primary outcomes
1
percentage of patients with recurrence free survival
RFS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
Time frame
5 years2
percentage overall survival
OS proportions to be calculated at 1, 3, and 5 years with Kaplan Meier analysis
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov