Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age45-75
SponsorUniversity Health Network, Toronto
About this trial
The goal of this observational study is to learn whether the healthy lifestyle choices made around surgery can influence an individual's long term risk of developing cardiovascular disease. Patients will be observed 1-month prior to and 3-months following surgery to assess their risk of developing cardiovascular disease.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 45 - 75 years
Scheduled for intermediate- to high risk non-cardiac surgery (intra-thoracic or intra-abdominal surgery, all vascular surgery, intra-cranial neurosurgery, spine surgery)
Expected post-operative length of stay of at least two days, according to the surgeon's expectation
Disqualifiers
Currently participating in a CVD risk reduction program
Patient is scheduled to undergo transplant or has undergone emergency surgery
Life expectancy <1 year (palliative surgery)
Recent (<6 months) myocardial infarction or stroke
Trial population
Non-cardiac surgery patients
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Healthy lifestyle behaviors around the time of surgery
BehavioralHealthy lifestyle choices, such as improving diet and beginning to exercise around the time of surgery and it's influence on an individual's long term risk of developing cardiovascular disease.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Baseline assessment for calculating the pre-operative 10-year CVD event risk
For the baseline assessment, the expected 10-year CVD event risk of each participant will be calculated according to the appropriate CVD event risk prediction score using blood tests, questionnaire to estimate an individual's functional capacity, blood pressure, heart rate and ECG.
Time frame
1 month before surgery2
Follow-up assessment for calculating the post-operative 10-year CVD event risk
For the follow-up assessment, the expected 10-year CVD event risk of each participant will be calculated according to the appropriate CVD event risk prediction score using blood tests, questionnaire to estimate an individual's functional capacity, blood pressure, heart rate and ECG.
Time frame
3 months after surgerySecondary outcomes
1
Occurrence of Cardiovascular or Non-Cardiovascular event
Cardiovascular related (e.g. Myocardial infarction/injury, mortality, heart failure) or non-cardiovascular related (e.g. surgical site infections, unexpected critical care unit admissions, re-operations).
Time frame
30 days after surgerySponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov