Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-47
SponsorCentre Hospitalier Universitaire, Amiens

About this trial

Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity.

Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.

However, few studies have analyzed the long-term reproductive outcomes of these interventions, nor how patients ultimately use or do not use the FP options once in remission.

This project aims to better understand the effectiveness, utilization, and psychological impacts of these strategies.

This work is part of an effort to understand and evaluate fertility preservation practices implemented for women of reproductive age undergoing cancer treatment at the Amiens-Picardie University Hospital (CHU).

Its objective is to document patient pathways, clinical decisions, techniques employed, and reproductive outcomes observed after remission, in order to identify potential areas for improvement in the support and follow-up of these patients, thereby enhancing the overall quality and coordination of care.

This work is conducted alongside the development of a fertility observatory at the Department of Medicine and Reproductive Biology, CHU Amiens-Picardie.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Women

Aged between 18 and 47 years

Diagnosed with cancer or hematological disorders requiring potentially gonadotoxic treatment

Having undergone a medical fertility preservation consultation

Disqualifiers

Absence of remission

Patients deprived of liberty by administrative or judicial decision, or placed under legal protection (guardianship or curators)

Decline to participate in the study

Trial population

Patients are recruited during follow-up consultations as part of the establishment of a fertility observatory within the Department of Medicine and Reproductive Biology at CHU Amiens Picardie

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Occurrence of an identifiable reproductive outcome

Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project

Time frame
1 year

Secondary outcomes

1

Type of fertility preservation method performed

Time frame
1 year
2

Time interval (in months) between diagnosis and fertility preservation

Time frame
1 year
3

Correlation between Age and occurance of an identifiable reproductive outcome

Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project

Time frame
1 year
4

Time interval (in months) between fertility preservation and initiation of potentially gonadotoxic treatment

Time frame
1 year

Other outcomes

Sponsors and contacts

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