Low-Flow Anesthesia and Open-Heart Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorÇağrı Özdemir
About this trial
Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R. Virtue defined minimal flow anesthesia (MFA) as 0.5 L/min. In 1984, Baker and Simionescu classified LFA as 0.5-1 L/min and MFA as 0.25-0.5 L/min. The aim of this study is to investigate whether there are hemodynamic differences between open-heart surgery cases performed with LFA at different fresh gas flow rates.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Emergency cases
Patients under 18 years of age
Patients who have had open heart surgery before
Patients for whom the use of inhaled anesthetic agents is contraindicated
Trial population
≥18 years and scheduled for open-heart surgery patients
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
80 Participants
are grouped into 4 trial groupsGroup A: Group 1
Group B: Group 2
Group C: Group 3
Group D: Group 4
Trial outcomes
Primary outcomes
1
physiological parameter ; heart rate
Heart rate will be recorded every 10 minutes, expressed as beats per minute, starting before induction and including the sternotomy and pericardiotomy periods.
Time frame
Intraoperatively2
physiological parameter; systolic/diastolic blood pressure
Systolic and diastolic blood pressure will be recorded every 10 minutes in mmHg, starting before induction and including the sternotomy and pericardiotomy periods.
Time frame
Intraoperatively3
physiological parameter; SpO2
SpO2 will be recorded as a percentage every 10 minutes, starting before induction and including the sternotomy and pericardiotomy periods.
Time frame
Intraoperatively4
Monitoring parameter; Bispectral Index (BIS)
The BIS value will be recorded numerically every 10 minutes, starting from before induction and including the sternotomy and pericardiotomy periods.
Time frame
IntraoperativelySecondary outcomes
1
Preoperative data; ASA (American Society of Anesthesiologists) classification
During the preoperative period, preoperative data, including the American Society of Anesthesiologists (ASA) Physical Status Classification, will be recorded. The ASA classification is used to assess the patient's preoperative physical status and perioperative risk, with higher ASA classes (I-IV) indicating increased systemic disease severity and perioperative risk.
Time frame
24 hours before surgery2
Preoperative data
In the preoperative period, the degree of valve dysfunction (such as I.degree TY, II.degree MY) of the patients will be recorded.
Time frame
24 hours before surgery3
Preoperaitive data
In the preoperative period, the patient's ejection fraction will be recorded as a percentage.
Time frame
24 hours before surgerySponsors and contacts
Click on the lead sponsor to view all of their trials.
Çağrı Özdemir
Lead sponsor
Gazi University
Sponsor institution
Source ClinicalTrials.gov