Low-value Care, and Variation in Practice for Children Hospitalized With Bronchiolitis

ConditionBronchiolitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age28-12
SponsorSt. Justine's Hospital

About this trial

Low-value care is defined as the use of a health service, such as diagnostics and treatments, for which the harms or costs outweigh the benefits. In pediatrics, investigations or treatments can be unpleasant or traumatizing to the child, can prolong the time spent in hospital, and can create a cascade of further futile investigations and treatments. Several of the commonly used diagnostics and treatments in bronchiolitis are considered low-value, making it a great model to study low-value care in pediatrics.

The purpose of CareBEST is to study the use of 6 low-value healthcare services in children aged 1 to 12 months hospitalized with bronchiolitis, their costs, and measure the variability in practice of these services.

The main questions this study aims to answer are:

1. How frequently are 6 low-value care health services used in children hospitalized with bronchiolitis? These 6 low-value care health services are: 1) respiratory virus testing; 2) chest x-rays; 3) continuous pulse oximetry; 4) short-acting beta-agonists; 5) systemic corticosteroids; and 6) antibiotics.

* Are there factors that predict the use of these services? * What are the costs of the use of these services? 2. How much variability is there between different patients, different doctors, and between hospitals in the use of these 6 low-value health services ? 3. Are differences in use of low-value health services associated with patient and family characteristics (like race and ethnicity, socioeconomic status, language), and do these contribute to disparities in care?

Participants will have their infant's medical chart reviewed during their hospitalization. They will also have 2 short questionnaires to complete, once during their child's admission to the hospital, and one 30 days later to ask about whether their child required any additional medical care. They will additionally be asked to complete a questionnaire on their perceptions regarding their child's care while hospitalized, including the use of shared-decision making and their understanding of and involvement in the care decisions made.

This analysis will provide a better understanding of treatment of bronchiolitis in Canada and help in the development of effective interventions to reduce low-value care.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Children aged >28 days to <12 months

Children admitted to a pediatric inpatient ward with an admission diagnosis of bronchiolitis

Disqualifiers

None

Trial population

Children aged \>28 days to \<12 months with an admission diagnosis of bronchiolitis.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Provision of any of six different low-value health services for treatment of bronchiolitis

    Diagnostic test

    This prospective observational will have six separate primary outcomes acting as exposures, (or interventions).The exposures are the the provision of any of the six low-value health services: 1) respiratory virus testing; 2) chest x-ray; 3) continuous pulse oximetry; 4) short-acting beta-agonists; 5) systemic corticosteroids; and 6) antibiotics.

Treatment groups

3,000 Participants
are divided into 15 treatment groups

15

Treatment groups

See each treatment group below.

Group A: Children admitted to CHU Sainte-Justine1 intervention
Group B: Children admitted to McMaster Children's Hospital1 intervention
Group C: Children admitted to British Columbia Children's Hospital1 intervention
Group D: Children admitted to IWK Children's Hospital1 intervention
Group E: Children admitted to CHU de Quebec University Laval Hospital1 intervention
Group F: Children admitted to Montreal Children's Hospital1 intervention
Group G: Children admitted to Children's Hospital of Eastern Ontario1 intervention
Group H: Children admitted to Kingston Health Sciences Centre1 intervention
Group I: Children admitted to The Hospital for Sick Children0 interventions
Group J: Children admitted to Children's Hospital of Western Ontario1 intervention
Group K: Children admitted to Alberta Children's Hospital1 intervention
Group L: Children admitted to Stollery Children's Hospital1 intervention
Group M: Children Admitted to Hôpital Maisonneuve-Rosemont1 intervention
Group N: Children admitted to Cité-de-la-Santé1 intervention
Group O: Children admitted to Lakeridge Health1 intervention

Trial outcomes

Primary outcomes

1

The proportion of eligible patients receiving each of the six low-value health services

The primary outcome of the study is the proportion of patients receiving each of the six low-value health services during their hospitalization for bronchiolitis: 1) respiratory virus testing; 2) chest x-ray; 3) continuous pulse oximetry; 4) short-acting beta-agonists; 5) systemic corticosteroids; and 6) antibiotics.

Time frame
24 months

Secondary outcomes

1

Transfer to the ICU

Whether the child admitted with bronchiolitis was transferred to the ICU. If so, duration of ICU stay.

Time frame
24 months
2

Use of CPAP, BiPAP, or mechanical ventilation during admission.

Use of continuous positive airway pressure (CPAP) or biphasic positive airway pressure (BiPAP), mechanical ventilation during admission, as documented in patient's admission record.

Time frame
24 months
3

Cardiac arrest

Whether the child experienced a cardiac arrest during their admission.

Time frame
24 months
4

Death

Whether the child died during their admission.

Time frame
24 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

St. Justine's Hospital

Lead sponsor

Children's Hospital of Eastern Ontario

Collaborator

Maternal Infant Child and Youth Research Network

Collaborator

The Hospital for Sick Children

Collaborator

Unity Health Toronto

Collaborator