About this trial
Low-value care is defined as the use of a health service, such as diagnostics and treatments, for which the harms or costs outweigh the benefits. In pediatrics, investigations or treatments can be unpleasant or traumatizing to the child, can prolong the time spent in hospital, and can create a cascade of further futile investigations and treatments. Several of the commonly used diagnostics and treatments in bronchiolitis are considered low-value, making it a great model to study low-value care in pediatrics.
The purpose of CareBEST is to study the use of 6 low-value healthcare services in children aged 1 to 12 months hospitalized with bronchiolitis, their costs, and measure the variability in practice of these services.
The main questions this study aims to answer are:
1. How frequently are 6 low-value care health services used in children hospitalized with bronchiolitis? These 6 low-value care health services are: 1) respiratory virus testing; 2) chest x-rays; 3) continuous pulse oximetry; 4) short-acting beta-agonists; 5) systemic corticosteroids; and 6) antibiotics.
* Are there factors that predict the use of these services? * What are the costs of the use of these services? 2. How much variability is there between different patients, different doctors, and between hospitals in the use of these 6 low-value health services ? 3. Are differences in use of low-value health services associated with patient and family characteristics (like race and ethnicity, socioeconomic status, language), and do these contribute to disparities in care?
Participants will have their infant's medical chart reviewed during their hospitalization. They will also have 2 short questionnaires to complete, once during their child's admission to the hospital, and one 30 days later to ask about whether their child required any additional medical care. They will additionally be asked to complete a questionnaire on their perceptions regarding their child's care while hospitalized, including the use of shared-decision making and their understanding of and involvement in the care decisions made.
This analysis will provide a better understanding of treatment of bronchiolitis in Canada and help in the development of effective interventions to reduce low-value care.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Children aged >28 days to <12 months
Children admitted to a pediatric inpatient ward with an admission diagnosis of bronchiolitis
Disqualifiers
None
Trial population
Children aged \>28 days to \<12 months with an admission diagnosis of bronchiolitis.
Trial design
Cohort
Prospective
Treatments tested in this trial
Provision of any of six different low-value health services for treatment of bronchiolitis
Diagnostic testThis prospective observational will have six separate primary outcomes acting as exposures, (or interventions).The exposures are the the provision of any of the six low-value health services: 1) respiratory virus testing; 2) chest x-ray; 3) continuous pulse oximetry; 4) short-acting beta-agonists; 5) systemic corticosteroids; and 6) antibiotics.
Treatment groups
15
Treatment groupsSee each treatment group below.
Trial outcomes
Primary outcomes
The proportion of eligible patients receiving each of the six low-value health services
The primary outcome of the study is the proportion of patients receiving each of the six low-value health services during their hospitalization for bronchiolitis: 1) respiratory virus testing; 2) chest x-ray; 3) continuous pulse oximetry; 4) short-acting beta-agonists; 5) systemic corticosteroids; and 6) antibiotics.
Secondary outcomes
Transfer to the ICU
Whether the child admitted with bronchiolitis was transferred to the ICU. If so, duration of ICU stay.
Use of CPAP, BiPAP, or mechanical ventilation during admission.
Use of continuous positive airway pressure (CPAP) or biphasic positive airway pressure (BiPAP), mechanical ventilation during admission, as documented in patient's admission record.
Cardiac arrest
Whether the child experienced a cardiac arrest during their admission.
Death
Whether the child died during their admission.
Sponsors and contacts
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St. Justine's Hospital
Lead sponsor
Children's Hospital of Eastern Ontario
Collaborator
Maternal Infant Child and Youth Research Network
Collaborator
The Hospital for Sick Children
Collaborator
Unity Health Toronto
Collaborator