The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease. The main question it aims to answer are:
\- what are the cut-off values for non-invasive tests (NITs) (including LSM, SSM) that predict the presence and occurrence of hepatic decompensation in individuals with advanced chronic liver disease?
Participants will undergo regular study visits involving non-invasive tests (LSM, SSM) and assessments to monitor hepatic decompensation over the study period.
Age above 18years old
Advanced chronic liver disease (defined as LSM ≥ 10kPa)
Ability to provide informed consent
Transjugular intrahepatic portosystemic shunt
previous liver transplantation
Abnormality of the porto-mesenteric system (portal vein thrombosis, splenic vein thrombosis, splenectomy, portal cavernomatous transformation, porto-caval shunts)
Hematological malignancy
Adults with advanced chronic liver disease (defined as LSM ≥ 10kPa)
Cohort
Prospective
Not listed
Number of patients diagnosed with portal hypertension using elastography techniques
We will assess the diagnostic accuracy of liver and spleen stiffness measurements for portal hypertension
Identifying patients at high-risk of liver related events using elastography techniques
We will use liver and spleen stiffness measurements to identify patients at risk of developing liver -related events
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