Study design: prospective, single arm.
Objectives: survey lung cancer detection rate of low-dose computed tomography (LDCT) screening in individuals who had never smoked.
Participants will undergo questionnaires, and collecting specimens including blood, urine, and medical informations including results of pulmonary function tests, and LDCT screening upon inclusion. The participants will be followed up according to current standards of clinical practice.
Individuals with no history of smoking.
Aged 40 to 80 years.
Willing to provide written informed consent and complete questionnaire assessments.
After undergoing examinations, willing to provide relevant biological information, including but not limited to: blood samples, urine samples, pulmonary function test results, imaging data, and tissue specimens obtained from invasive biopsies or surgical procedures (if applicable).
History of lung cancer, or a diagnosis of any malignancy other than skin cancer or cervical carcinoma in situ within the past five years.
Undergoing chest computed tomography (CT) scans within the past 18 months.
Unexplained hemoptysis within the past one month.
Unexplained weight loss exceeding 6 kilograms within the past one year.
Single group
Low dose computed tomography
Diagnostic testLow dose computed tomography for lung cancer screening
Lung cancer detection rate
The rate of lung cancer diagnosis during follow up periord.
AUROC of FORMOSA Lung Cancer Risk Prediction Model
Assess the sensitivity, specificity, positive predicting value, negative predicting value, and ROC analysis of FORMOSA Lung Cancer Risk Prediction Model
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Chung Shan Medical University
Lead sponsor
Ministry of Health and Welfare, Taiwan
Collaborator
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