About this trial
This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery.
The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented.
Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels.
The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Preeclampsia with severe features.
Gestational age 24 weeks - 41 weeks.
Disqualifiers
Chronic lung disease.
Known heart disease.
Diagnosis of lung edema at admission
Body mass index > 40
Trial design
Single group
Treatments tested in this trial
Lung ultrasound
Diagnostic testLung ultrasounf at three moments (at admission, before delivery and immediate post partum) to determine B Lines
Treatment groups
Trial outcomes
Primary outcomes
Lung Ultrasound evaluation
Three or more B Lines in at least two lung zones using lung ultrasound
Secondary outcomes
Dyspnea
Subjective sensation of difficulty breathing
Tachypnea
Respiratory rate above 20 breaths/min
Oxygen saturation
Oxygen saturation measured by pulse oxymeter
Sponsors and contacts
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