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Magnetoencephalography by Optical Pumping Magnetometer

ConditionsMagnetoencephalographyOptical Pump MagnetometerNeonatePremature
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1+
SponsorCentre Hospitalier Universitaire, Amiens

About this trial

MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG). The main limitation of MEG is its cost due to the sensors used, the Super Quantum Interference Devices (SQUID). These require a complex infrastructure from an instrumentation point of view to operate, requiring liquid helium, most often at a loss, at increasing cost. Optical Pumping Magnetometers (OPM) type sensors represent a promising alternative to SQUIDs sensors, especially since they do not require helium cooling.

The purpose of this project is to Identify biomarkers in Magnetoencephalography of normal brain development in healthy adults, premature and term newborns from "a priori" obtained by the classical technique of High Resolution EEG performed.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

For healthy adult volunteers

Age between 18 and 65

No pathology, no treatment

No toxicant intake

Disqualifiers

Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible.

Patients who cannot stand to stand still for a few minutes.

Newborn on ventilatory assistance or infusion

Newborn baby not meeting the age criteria

Trial design

Design model

Parallel

Treatments tested in this trial

  • Magnetoencephalography

    Other intervention

    40 minutes of Magnetoencephalography with Optical Pump Magnetometer

Treatment groups

70 Participants
are divided into 4 treatment groups
Group A: AdultsExperimental treatment 1 intervention
Group B: full term neonatesExperimental treatment 1 intervention
Group C: premature neonatesExperimental treatment 1 intervention
Group D: pregnant womenExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Signal to noise ratio of the MEG OPM

Signal to noise ratio of the MEG OPM is in dB

Time frame
1 day
2

Signal to noise ratio of HR EEG

Signal to noise ratio of HR EEG is in dB

Time frame
1 day
3

Number of dB between Signal to noise ratio of the MEG OPM and Signal to noise ratio of HR EEG

Time frame
1 day

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Centre Hospitalier Universitaire, Amiens

Lead sponsor

Source ClinicalTrials.gov
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