Manual- VS Auto-Strain

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-99
SponsorBruno Mora

About this trial

Myocardial strain analysis provides additional and valuable information about left ventricular function, particularly in the perioperative setting with its dynamic changes in ventricular load conditions. This allows for earlier risk assessment and, if necessary, the initiation of faster and more targeted therapy. Unfortunately, conventional strain analysis using conventional methods currently takes approximately 5 minutes. However, this amount of time is often not available in a dynamically changing intraoperative setting during cardiac surgery. Therefore, the benefits of strain analysis have not yet been routinely utilized during the intraoperative course. However, new software solutions exist that can perform strain analysis fully automatically and reduce the examination time to a few seconds. However, it remains unclear whether these fully automated analyses also function reliably intraoperatively using transesophageal echocardiography (TEE). The aim of this study is to assess the reliability of these new methods.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult (≥18 years) cardiac surgery patients

Sinus rhythm

No severe valvular regurgitation

Use of General Electric (GE) echocardiography systems (Vivid S60, S70, E95) and corresponding EchoPAC software as well as TOMTEC software.

Disqualifiers

Inadequate image quality

Any severe heart valve regurgitation

Mechanical circulatory support systems (e.g., LVAD, Impella, ECMO)

Trial population

Patients undergoing cardiac surgery who are monitored with a transesophageal echocardiography probe

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Correlation between conventionally measured global longitudinal strain (GLS) and fully automated global longitudinal strain (Auto-GLS)

Time frame
1-3 days

Secondary outcomes

1

Correlation between fully automated global longitudinal strain measured using GE EchoPac (GE-Auto-GLS) and fully automated global longitudinal strain measured using TOMTEC AutoStrain (TOMTEC Auto-GLS)

Time frame
1 day

Other outcomes

Sponsors and contacts

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Bruno Mora

Lead sponsor

Medical University of Vienna

Sponsor institution