Manual Debridement vs Phototherapeutic Keratectomy in the Treatment of Corneal Basement Membrane Dystrophy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre hospitalier de l'Université de Montréal (CHUM)

About this trial

Of the few comparisons made in the existing literature, the results of PTK are comparable to those documented for manual debridement (MD). However, the shorter length of follow-up in patients with MD may have underestimated the associated complications. Our study, therefore, aims to offer a comparison between these two techniques to clarify the choice of effective treatment with a good safety profile.

Eligibility criteria

Qualifiers

Patient over 18 years of age;

Ability to give free and informed consent

At least 1-year follow-up possible

Patients with bilateral basal membrane corneal dystrophy who are symptomatic (recurrent corneal erosions, visual disturbances) and are candidates for bilateral surgery.

Disqualifiers

Patient under 18 years of age;

History of ocular infection with herpes simplex virus.

Trial design

Treatments tested in this trial

  • Manual debridement
  • Phototherapeutic keratectomy

Treatment groups

25 Participants
are divided into 2 treatment groups