Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorNorthwestern University

About this trial

This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults aged at least 18y

Able to perform shoulder abduction task (confirmed during screening and initial examination)

Safe to undergo MRI

Able to follow visual instructions using MRI-compatible vision correction goggles

Disqualifiers

MRI contraindications

Severe claustrophobia

Pregnant women

Prisoners

Trial design

Design model

Single group

Treatments tested in this trial

  • Shoulder Abduction

    Other intervention

    Individuals will be visually cued to perform short, unilateral, isometric shoulder abduction tasks. A visual display will provide real-time feedback of the shoulder abduction torque, to help the participant target a predetermined torque level.

Treatment groups

32 Participants
are divided into 1 treatment group
Group A: Shoulder AbductionExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

BOLD activation

BOLD fMRI data will be analyzed to map neural activation associated with the shoulder abduction task.

Time frame
3 days to 3 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Northwestern University

Lead sponsor

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborator