Mapping of Electrical Properties in the Brain
ConditionMalignant Glioma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMayo Clinic
About this trial
This study evaluates imaging methods for monitoring neural and electrical activity in the brain for improving clinical diagnosis.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aim 1: normal healthy volunteers
Aim 2, 3, 4: participants included in IRB 16-002424, including those that have undergone surgical biopsy/resection for suspected or known glioma
Disqualifiers
Healthy volunteer unable to have an MRI
Trial population
Healthy volunteers and clinical neuro-oncology subjects with high grade glioma
Trial design
Design model
Case-control
Time perspective
Cross-sectional
Treatments tested in this trial
Non-Interventional Study
Other interventionNon-interventional study
Treatment groups
120 Participants
are divided into 1 treatment groupGroup A: Observational1 intervention
Trial outcomes
Primary outcomes
1
Identify diffusion MRI metrics [using conductivity tensor imaging (CTI)] that inform of regional electrical properties in the brain
At least 4 normal white matter regions of the brain will be analyzed. Fractional anisotropy (FA) and optimized diagnostic imaging (ODI) values will be compared to determine alignment within normal healthy white matter tracts (e.g. cortical spinal tract, corpus callosum).
Time frame
BaselineSponsors and contacts
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Source ClinicalTrials.gov