This is a registry study that aims to collect patients' data with advanced-stage rare cancer in Asia-Pacific region. Data includes clinical information, details of treatment, prognosis, pathological diagnosis and genetic biomarkers by next-generation sequencing.
The relationship between cancer types and prognosis, the effect of treatments, and the cancer type-specific incidence of genomic alterations will be investigated to discover more specific and effective treatment.
Patients with a histological diagnosis of rare cancer, cancer of unknown primary origin, or cancer of rare tissue subtypes of common cancers. (Defined in protocol.)
Patients with Advanced stage cancer.
None
Malignancies with an annual incidence of less than 6 cases per 100,000 population; malignancies categorized as rare cancers in the European RARECARE report; malignancies that are difficult to develop treatments; common cancers with rare tissue subtypes; common cancers that can be regarded as rare based on biological demographics such as age or sex; and cancers of unknow primary are eligible for this study.
Other
Prospective
Genomic sequence
Other interventionGenomic sequence
Overall incidence of any genomic alteration in overall population
Overall incidence of any genomic alteration in overall population
Overall incidence of any genomic alteration in patients with a certain cancer type
Overall incidence of any genomic alteration in patients with a certain cancer type
Incidence of individual genomic alteration in overall population
The incidence of individual genomic alterations in overall population
Incidence of individual genomic alteration in patients with a certain cancer type
The incidence of individual genomic alterations in patients with a certain cancer type
Biomarker positive proportion in overall population
The proportion of patients positive for certain biomarkers in overall population
Biomarker positive proportion in patients with a certain cancer type
The proportion of patients positive for certain biomarkers in patients with a certain cancer type
Number of somatic variants within exons in overall population
The number of somatic variants and proportion of variants in overall population
Number of somatic variants within exons in patients with a certain cancer type
The number of somatic variants and proportion of variants in patients with a certain cancer type
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