Maternal Autoimmune Disease Research Alliance (MADRA) Registry

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorDuke University

About this trial

This multi-site registry, centered at Duke University, will enroll pregnant women with autoimmune and rheumatologic diseases.

The main goal of MADRA is to identify ways to improve the health of women with rheumatic diseases and their babies during pregnancy.

Prior studies demonstrate the importance of increase inflammation prior to and during pregnancy on these outcomes. The future research will seek to better define these risk factors and to identify ways to may improve them.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Desire for pregnancy within 6 months or currently pregnant

Lupus (systemic lupus erythematosus or cutaneous lupus)

Antiphospholipid Syndrome or positive antiphospholipid antibodies

Rheumatoid Arthritis

Disqualifiers

Unable to speak English

Unable to provide informed consent

Unable to travel to Duke University for follow-up visits

Trial population

Women who have been diagnosed with an autoimmune disease or a rheumatic condition.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

1,000 Participants
are grouped into 1 trial group
Group A: Maternal Autoimmune Disease ReseArch (MADRA) Registry

Trial outcomes

Primary outcomes

1

Risk factors associated with poor pregnancy outcomes as measured by the MADRA-DAP questionnaire.

The investigators will ask the participants questions from the MADRA-DAP questionnaire to determine poor pregnancy outcomes.

Time frame
up to 10 years

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.