Maternal Outcomes With Methamphetamine Use and Cardiac Assessment for Rural Dissemination (MOM CARD)

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-65
SponsorOregon Health and Science University

About this trial

The purpose of this study is to develop a pilot screening protocol, comparing cardiac point-of-care ultrasound (POCUS), electrocardiogram (EKG), serum biomarkers (N-terminal pro b-type natriuretic peptide (NT-proBNP), high sensitivity troponin (hsTn)) with formal transthoracic echocardiogram (TTE) in pregnant women with methamphetamine use.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18 years or older > 20 weeks gestation admitted to the hospital

Active patient-defined regular methamphetamine use for at least 1 year and any use within the last month

Able to understand and provide informed consent

Able to understand English

Disqualifiers

Prescribed stimulants

Echocardiogram or EKG previously performed during current pregnancy

Previous diagnosis of congestive heart dysfunction

Previous diagnosis of pulmonary hypertension

Trial population

Pregnant women \> or equal to 20 weeks gestation presenting to OHSU for hospital, day patient, or observation admission will be identified via the electronic medical record.

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Sensitivity of point of care cardiac ultrasound for the detection of left ventricular systolic dysfunction as compared to comprehensive transthoracic echocardiogram.

This outcome seeks to identify the sensitivity of point of care cardiac ultrasound for the identification of left ventricular systolic dysfunction in pregnant people who use methamphetamine when performed by an obstetrics provider, as compared to formal transthoracic echocardiogram.

Time frame
Day 1

Secondary outcomes

1

Sensitivity of cardiac biomarkers and ECG for the identification of left ventricular systolic dysfunction as compared to comprehensive transthoracic echocardiogram. methamphetamine

This outcome seeks to identify the sensitivity of N-terminal pro-B-type natriuretic peptide (NT-proBNP), high sensitivity troponin and electrocardiogram for the identification of left ventricular systolic dysfunction in pregnant people who use methamphetamine, as compared to formal transthoracic echocardiogram.

Time frame
Day 1
2

Prevalence of underlying structural heart disease in pregnant people who use methamphetamine

This outcome seeks to identify the prevalence of structural heart disease in pregnant people who use methamphetamine.

Time frame
Day 1
3

Pregnancy and delivery outcomes in people who use methamphetamine

This outcome seeks to identify the prevalence of pregnancy delivery complications in people who use methamphetamine.

Time frame
3 months postpartum
4

Changes to pregnancy-related treatment plan based on cardiovascular screening in people who use methamphetamine.

This outcome seeks to identify linkage to cardiovascular and addiction specialty care among patients diagnosed with cardiovascular disease.

Time frame
3 months postpartum

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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