Meals, Microbiota & Mental Health of Children & Adolescents

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age5-15
SponsorUniversity of Iceland

About this trial

Recent studies indicate that the interplay between diet, intestinal microbiota composition, and intestinal permeability might impact mental health. The aim of thisl study is to compare diet, intestinal microbiota, intestinal permeability, and related metabolic factors among children and adolescents diagnosed with mental health disorders and control groups and identify potential relationship patterns. All children and adolescents referred to the outpatient clinic at the Child and Adolescent Psychiatry Department at The National University Hospital in Reykjavik Iceland will be offered to participate (n=15) (age 5-15 years). Two control groups will be used; the same parent siblings close in age (n=x) as well as age and sex-matched children from the same postal area (n=15). A three-day food diary, rating scales for mental health and multiple questionnaires will be completed as well as faecal sample, buccal swab, urine, saliva and blood samples will be collected. This is a novel approach as more multidimensional transdisciplinary studies including longitudinal observational data have been called for as a basis for lifestyle treatment options for improving mental health and wellness.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

A diagnosis of mental health disorder (ICD10)

Antibiotics use for the last six months

Trial population

Children and adolescents (both genders; 5-15y) referred for their first visit to the outpatient clinic at the Child and Adolescent Psychiatry Department (BUGL) (n=150) will be invited to participate. Two control groups will be used; 1) Same parent siblings close in age to the study subjects (+3y) (n\<150) 2) Age and sex matched child from the same postal area (n=150).

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

30 Participants
are grouped into 3 trial groups
Group A: Cases
Group B: Contol
Group C: Syblings

Trial outcomes

Primary outcomes

1

Intestinal permeability

The prevalence of IP among cases

Time frame
One year

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Iceland

Lead sponsor

Landspitali University Hospital

Collaborator

This trial is not recruiting at the moment. You can still explore other options: