This prospective observational study evaluates the association between intraoperative mechanical power (MP) - a composite measure of the total energy delivered to the lungs during mechanical ventilation - and postoperative pulmonary complications (PPCs) and prolonged mechanical ventilation in adult patients undergoing elective coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass (CPB). Intraoperative ventilatory parameters including tidal volume, respiratory rate, airway pressures, and PEEP will be recorded and used to calculate MP and driving pressure (DP). No additional interventions will be applied beyond standard clinical care.
Age 18 years or older
Scheduled for elective, first-time isolated CABG surgery
Use of cardiopulmonary bypass (CPB)
Intraoperative mechanical ventilation applied under general anesthesia with recordable ventilator data
Emergency cardiac surgery
Off-pump CABG (without CPB)
Preoperative requirement for invasive mechanical ventilation
Advanced chronic lung disease
Adult patients undergoing elective isolated CABG surgery with cardiopulmonary bypass at a single tertiary cardiac surgery center
Cohort
Prospective
Intraoperative Mechanical Ventilation Monitoring
Other interventionIntraoperative ventilatory parameters (tidal volume, respiratory rate, plateau pressure, PEEP) are routinely recorded during CABG surgery. Mechanical power and driving pressure are calculated from these parameters. No additional intervention is applied beyond standard clinical care.
Postoperative Pulmonary Complication
Occurrence of at least one of the following within the first 48 hours postoperatively: atelectasis, pleural effusion, pneumonia, prolonged oxygen requirement, need for non-invasive ventilation (NIV), or re-intubation
Prolonged Mechanical Ventilation
Duration of mechanical ventilation greater than 24 hours
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Fusun Gozen
Lead sponsor
Bursa Yuksek Ihtisas Training and Research Hospital
Sponsor institution
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