Mechanical Ventilation in Surgical Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAzienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria

About this trial

This is an investigator-initiated, international, multicenter, prospective, cross-sectional study that aims to 1) describe the incidence and types of postoperative pulmonary complications (PPCs), 2) describe patient demographics, baseline characteristics, and intraoperative ventilation management, 3) describe the occurrence of intraoperative adverse events (IAEs), and 4) their associations with PPCs, 5) assess the practice of intraoperative mechanical ventilation.

Patients will be eligible for participation if: 1) adult and 2) receiving intraoperative ventilation during general anesthesia for surgery. Patients receiving ventilation outside of an operating room as well as patients receiving intraoperative ventilation during extracorporeal life support will be excluded

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults; and

Receiving intraoperative IMV (via tracheal intubation, or supraglottic device ) during general anesthesia for surgery

Disqualifiers

Receiving intraoperative IMV outside of an operating room; and

Receiving intraoperative IMV during extracorporeal life support

Trial population

Patients subjected to IMV during general anesthesia for surgery will be included in a consecutive manner

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Intraoperative mechanical ventilation for surgery

    Other intervention

    Any IMV during general anesthesia for surgery

Treatment groups

10,000 Participants
are divided into 1 treatment group
Group A: Intraoperative mechanical ventilation1 intervention

Trial outcomes

Primary outcomes

1

Postoperative pulmonary complications (PPCs)

Incidence and type of PPCs

Time frame
within 5 days after surgery

Secondary outcomes

1

Intraoperative adverse events (IAEs)

Incidence and type of IAEs

Time frame
Intraoperatively
2

Intraoperative mechanical ventilation practice

Mechanical ventilation settings in patients undergoing general anesthesia for surgery

Time frame
Intraoperatively
3

Postoperative clinical outcome

Hospital mortality

Time frame
Postoperatively, on day 28 following surgery

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria

Lead sponsor

University Of Perugia

Collaborator

University of Chieti

Collaborator

Medical University of Vienna

Collaborator

The Netherlands Cancer Institute

Collaborator

Monash University

Collaborator