Mechanism-Based Cervical Rehabilitation for Chronic Migraine
ConditionChronic Migraine
Trial statusEnrolling by invitation
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorBeni-Suef University
About this trial
To investigate the effectiveness of mechanism-based cervical sensorimotor rehabilitation on cervical muscle activation, cervical proprioception, and migraine burden.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Male or female adults aged 18-55 years. Diagnosed with chronic migraine according to the International Classification of Headache Disorders, Third Edition (ICHD-3), defined as headache occurring on ≥15 days per month for more than 3 months, with migraine features present on at least 8 days per month.
Disqualifiers
• Diagnosis of headache disorders other than chronic migraine (e.g., cervicogenic headache, cluster headache, or medication-overuse headache).
Trial design
Design model
Parallel
Treatments tested in this trial
cervical sensorimotor rehabilitation
Other interventionhe experimental group will receive an eight-week mechanism-based cervical sensorimotor rehabilitation programme consisting of deep cervical flexor training, cervical motor control exercises, laser-guided cervical joint position error retraining, eye-head coordination exercises, scapular neuromuscular stabilization exercises, and a structured home exercise programme. Treatment will be delivered three sessions per week, with each session lasting approximately 40 minutes.
conventional physiotherapy programme
Other interventionDescribe the conventional physiotherapy programme in the same level of detail as the experimental intervention, including exercise dosage, repetitions, duration, progression, and home programme.
Treatment groups
80 Participants
are divided into 2 treatment groupsGroup A: expermintalExperimental treatment 2 interventions
Group B: control groupActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
cervical joint position error
Cervical Joint Position Error (JPE) will be assessed to evaluate cervical proprioception using the Head Repositioning Accuracy Test. A lightweight laser pointer will be securely attached to the participant's head using an adjustable headband. Participants will be seated comfortably at a distance of 90 cm from a target grid mounted on a wall at eye level. At the beginning of each trial, participants will be instructed to identify and memorise their neutral head position while visually focusing on the centre of the target. They will then close their eyes and actively move their head to the end range of the required movement (flexion, extension, right rotation, left rotation, right lateral flexion, or left lateral flexion, depending on the testing protocol) before attempting to return to the original neutral position without visual feedback.The distance between the original target position and the repositioned laser point will be recorded and converted into angular error (degrees). Thre
Time frame
after the 8-week intervention, and at the 3-month follow-upSecondary outcomes
1
Headache Impact Test (HIT-6)
The Headache Impact Test (HIT-6) will be used to assess the impact of headaches on participants' daily functioning and health-related quality of life. The HIT-6 is a validated, self-administered questionnaire consisting of six items that evaluate headache-related limitations in pain severity, social functioning, role functioning, vitality, cognitive functioning, and psychological distress over the previous four weeks. Each item is scored using a five-point Likert scale with the following response options: Never = 6 points Rarely = 8 points Sometimes = 10 points Very Often = 11 points Always = 13 points The total score ranges from 36 to 78 points, with higher scores indicating a greater negative impact of headaches on daily life.
Time frame
after the 8-week intervention (Week 8), and at the 3-month follow-up2
Surface electromyographic (sEMG)
Surface electromyography (sEMG) will be used to assess the neuromuscular activity of the bilateral sternocleidomastoid (SCM) and upper trapezius (UT) muscles. Disposable Ag/AgCl bipolar surface electrodes will be placed over each muscle according to the Surface Electromyography for the Non-Invasive Assessment of Muscles (SENIAM) recommendations following skin preparation (shaving if necessary, light abrasion, and cleaning with alcohol). The primary sEMG variables will include the root mean square (RMS) amplitude (µV) of the muscle activation during each task. If maximal voluntary isometric contraction (MVIC) testing is feasible, RMS values will be normalized and expressed as a percentage of MVIC (%MVIC) to facilitate comparisons between participants. If MVIC normalization is not performed, RMS values will be reported in microvolts (µV). The mean value of the three trials will be used for statistical analysis. Surface EMG measurements will be obtained at baseline (Week 0), immediately
Time frame
baseline of 8-week intervention, and at the 3-month follow-upSponsors and contacts
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Source ClinicalTrials.gov