Mechanism Investigation of R-CHOP Regimen or Tucidinostat Plus R-CHOP (CR-CHOP) Regimen in the Treatment of BCL2/MYC Protein Double Expressor Lymphoma

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorRuijin Hospital

About this trial

This study is trying to explore the mechanism of R-CHOP regimen or tucidinostat plus R-CHOP (CR-CHOP) regimen in the treatment of BCL2/MYC protein double expressor lymphoma.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Each potential subject must satisfy all of the following criteria to be enrolled in the study.

Disqualifiers

Any potential subject who meets any of the following criteria will be excluded from participating in the study.

Trial population

Patients with accessible tissue samples were selected from a phase III study of tucidinostat in combination with R-CHOP in patients with newly diagnosed double expressor DLBCL (NCT04231448).

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Event Free Survival (EFS)

Defined as the duration from the date of randomization to the date of disease progression, relapse from CR , initiation of subsequent systemic antilymphoma therapy for residual disease, or death, whichever occurs first.

Time frame
Up to approximately 5 years

Secondary outcomes

1

Progression-Free Survival (PFS)

Defined as the duration from the date of randomization to the date of progression, relapse from CR, or death, whichever occurred first.

Time frame
Up to approximately 5 years

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: