Mechanisms of Fecal Incontinence in Wolfram Syndrome
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorHôpital Necker-Enfants Malades
About this trial
In order to clarify the mechanism of fecal incontinence in in Wolfram syndrome and to characterize its risk factors, the examiner will reviewed the files of patients followed in a Reference Center for Rare Diseases in Ophthalmology.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Wolfram syndrome
Disqualifiers
no information concerning fecal incontinence in data records
Trial population
retrospectif cohort of the rare disease center
Trial design
Design model
Case-control
Time perspective
Retrospective
Treatments tested in this trial
Retrospective case-control analysis
Other interventionretrospective analysis of data
Treatment groups
20 Participants
are divided into 2 treatment groupsGroup A: Wolfram syndrome patients with fecal incontience1 intervention
Group B: Wolfram syndrome patients without fecal incontience1 intervention
Trial outcomes
Primary outcomes
1
Urinary disorders
number of patients with urinary disorder in each group according to the group
Time frame
The date at the baselineSecondary outcomes
1
sleep apnea
number of patients with sleep apnea in each group according to the group
Time frame
The date the data will be analyzed at the baseline2
frequence of swallowing disroder
number of patients with swallowing disorders in each group according to the group
Time frame
The data will be analyzed at baseline3
frequence of diabetes insipidus
number of patients with diabetes insipidus in each group according to the group
Time frame
The data will be analyzed at baseline4
mutation type
report of mutations of WFS1 in each group
Time frame
The data will be analyzed at baselineSponsors and contacts
Click on the lead sponsor to view all of their trials.
Hôpital Necker-Enfants Malades
Lead sponsor
UF Ophthalmology HEGP
Sponsor institution
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: