Mechanisms Underlying Late-Life Prolonged Grief Disorder
ConditionProlonged Grief Disorder
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-89
SponsorMedical College of Wisconsin
About this trial
After losing a loved one, most successfully navigate acute grief and adapt to the loss within about 1 year, but in about 10%, prolonged grief disorder (PGD) ensues. This study is anticipated to provide novel evidence regarding the neurobiological mechanisms of PGD in older adults. The biological alterations identified here could provide targets to elucidate how currently available therapies work and inform novel mechanism-based interventions for treating late-life PGD.
Eligibility criteria
Qualifiers
Male or female greater than or equal to 40 years of age
Bereavement >6 months
Score greater than or equal to 25 on the Inventory of Complicated Grief (ICG)
Presence of PGD (subsyndromal and syndromal)
Disqualifiers
Delirium/unstable medical conditions
Lifetime history of neurological illnesses: seizures, stroke, dementia of any -etiology, severe head injury, brain tumor or surgery
Serious back, joint or neck injuries within the past 3 months
Currently practicing yoga
Trial design
Treatments tested in this trial
- Iyengar Yoga
- Health Education Control
- Waitlist Control to Crossover
Treatment groups
126 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov