This study is to find out whether and how a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity in healthy adults. A structural MRI scan will be used to customize where the stimulation electrodes are placed for each participant to deliver TES-TI during three afternoon sessions at rest with eyes closed. Brain activity is recorded with high-density EEG. Up to 24 participants will be enrolled and on study for 3 to 12 weeks.
Medically healthy (based on self-report and study team review)
U.S. citizen or holding permanent resident status
English-speaking (able to provide consent and complete questionnaires)
Current or past history of clinically significant neurological disorder or acquired neurological disease (e.g., stroke, traumatic brain injury), including intracranial lesions (including clinically significant findings identified on the structural MRI)
History of inpatient psychiatric hospitalization
History of head trauma resulting in prolonged loss of consciousness; or a history of >3 grade I concussions
Current poorly controlled headaches, including intractable or frequent migraines