The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. These monitors stimulate the ulnar nerve in the wrist and examine the evoked muscle response. The aim of this study is to examine the usability of another nerve in the wrist, the median nerve.
ASA I-III physical status
elective surgery requiring muscle relaxation
both arms are available during surgery in the same position for neuromuscular blockade monitoring
signed informed consent form
neruomuscular disorder in patient history (eg. stroke, myasthenia)
innervation problem in either arms (eg. carpal tunnel syndrome)
deformity to either arms (eg. Dupyurten contracture, severe arthritis)
Severe hepatic or renal insufficiency that affects muscle relaxant pharmacokinetics
Adult patients undergoing elective surgery that requires one dose of non-depolarising neuromuscular blocking agent, whose arms are accessible for intraoperative neuromuscular blockade monitoring.
Cohort
Prospective
Electromyography
Diagnostic testElectromyographic examination of the median and ulnar nerves to monitor intraoperative neuromuscular blockade
CMAP
Comparison of compound muscle action potential amplitudes evoked by median and ulnar nerve stimulation and measured at the thenar
Recovery time
Time from muscle relaxant administration to spontaneous recovery to TOFR\>0,9 monitored with median and ulnar nerve stimulation
Onset time
Time from administration of muscle relaxant to disappearance of twitch response (TOFC0) monitored with median and ulnar nerve stimulation
Bland-Altman analysis of TOFRs
Bland-Altman analysis of TOFRs obtained with medin and ulnar nerve stimulation
Bland-Altman analysis of TOFCs
Bland-Altman analysis of TOFCs obtained with median and ulnar nerve stimulation
Bland-Altman analysis of PTCs
Bland-Altman analysis of PTCs obtained with median and ulnar nerve stimulation
Baseline TOFRs
Examination of the stability of baseline TOFRs obtained with median and ulnar nerve stabilization
Click on the lead sponsor to view all of their trials.
Pongrácz Adrienn
Lead sponsor
University of Debrecen
Sponsor institution
