SELECT LATE trial aims to evaluate if addition of endovascular thrombectomy to medical management in patients presenting with acute ischemic stroke and a proximal large vessel occlusion in the anterior circulation between 24 and 72 hours of stroke onset results in achieving better functional outcomes (measured using modified Rankin Scale Scores) at 90-day follow-up (± 15 days).
Adults (18-85* years) with the final diagnosis of an acute ischemic stroke$
NIHSS ≥ 6
Time from last-known-well to randomization >24 - 72 hours
Pre-stroke modified Rankin Scale score of 0-1
Current participation in another investigational interventional drug or device study.
Baseline Platelet count <100,000/μl
Proven large vessel occlusion in ICA or MCA-M1 occlusion (carotid occlusions can be cervical or intracranial, with or without tandem MCA lesions), as determined by MR Angiography (MRA) or CT Angiography (CTA)
CT ASPECTS 3-10
Amrou Sarraj
Lead sponsor
University Hospitals Cleveland Medical Center
Sponsor institution
Patient-Centered Outcomes Research Institute
Collaborator