About this trial
A varicocele is defined as an abnormal venous dilatation and/or tortuosity of the pampiniform plexus in the scrotum. Although varicoceles are almost always and more common on the left side, up to 50% of the men with varicocele, have bilateral varicoceles.
Varicocele has a negative impact on spermatogenesis, testicular volume, Standard semen parameters, and fertilization, implantation, and embryo outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Sub-fertile men with clinically palpable varicoceles ( unilateral or bilateral ).
Men with teratozoospermia.
Disqualifiers
Recurrent varicoceles.
Significant medical diseases as: Hepatic insufficiency.
Hypersensitivity to the drugs.
Female factor of infertility.
Trial design
Parallel
Treatments tested in this trial
l-carnitine
Drugto compare the efficacy of medical treatment (l-carnitine and antioxidants) versus surgical treatment (varicocelectomy) versus surgical treatment and medical treatment (varicocelectomy with adjuvant medications) on pregnancy rate on varicocele related subfertility patients with isolated teratozoospermia.
Treatment groups
Trial outcomes
Primary outcomes
Number of participants with Treatment of Teratozoospermia
Treatment of the male patients that suffering from abnormally shaped sperms (Teratozoospermia) by medical treatment and or subinguinal varicocelcetomy
Sponsors and contacts
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