About this trial
The goal of this clinical trial is to learn if melatonin can decrease emergence agitation in pediatric post tonsillectomy. The main questions it aims to answer are:
Does melatonin decrease emergence agitation in pediatric post tonsillectomy? What medical problems do participants have when taking melatonin? Researchers will compare melatonin to a placebo (a look-alike substance that contains no drug) to see if melatonin works todecrease emergence agitation in pediatric post tonsillectomy
Participants will receive Oral melatonin at a dose of 0.5 mg/kg (maximum 20 mg) administered 30 minutes before induction of anesthesia. Dose chosen based on prior pediatric studies and safety data.
Eligibility criteria
Qualifiers
American Society of Anesthesiologists (ASA) physical status I or II.
Parent/legal guardian provides written informed consent
Disqualifiers
• Known allergy or contraindication to melatonin.
Pre-existing neurological or psychiatric disorders (e.g., epilepsy, autism, ADHD).
Children receiving any sedative or psychoactive medication within 48 hours of surgery.
Emergency surgery or any procedure other than tonsillectomy/adenoidectomy.
Trial design
Treatments tested in this trial
- Melatonin
- Placebo