About this trial
Episodic memory is our ability to remember personal experiences, such as a birthday party or a visit to the park. This study aims to understand how this type of memory develops during the first two years of a baby's life. Researchers will use a safe, non-invasive brain scanning technique called magnetic resonance imaging (MRI) to study healthy babies from birth until they are two years old. By following the same children over time, researchers will see how the brain's memory system develops and how it becomes connected with other parts of the brain. The findings will help us understand how babies develop the ability to remember personal experiences. They will also provide new knowledge about how the human brain develops during the earliest stages of life.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Infants born at the John Radcliffe Hospital, Oxford
Infants born at or after 35+0 weeks gestation
Infants with a postnatal age of <7 days
Infants for whom parents/legal guardians have given written informed consent for participation.
Disqualifiers
Hypoxic Ischaemic Encephalopathy (HIE)
Intraventricular haemorrhage (IVH) > grade II
Received any analgesics or sedatives in the last 24 hours
Congenital malformation or genetic condition known to affect neurological development
Trial population
Participants in this study will be infants born at the John Radcliffe Hospital, Oxford at or after 35+0 weeks gestation with a postnatal age of \<7 days.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
FMRI connectivity
Differences in functional connectivity of spontaneous fMRI brain activity
Secondary outcomes
Changes in fMRI connectivity
Longitudinal changes in fMRI connectivity over the entire duration of the study
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: