MEMRI: Memory Emergence Using MRI

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0-1
SponsorPaediatric Neuroimaging Research Group

About this trial

Episodic memory is our ability to remember personal experiences, such as a birthday party or a visit to the park. This study aims to understand how this type of memory develops during the first two years of a baby's life. Researchers will use a safe, non-invasive brain scanning technique called magnetic resonance imaging (MRI) to study healthy babies from birth until they are two years old. By following the same children over time, researchers will see how the brain's memory system develops and how it becomes connected with other parts of the brain. The findings will help us understand how babies develop the ability to remember personal experiences. They will also provide new knowledge about how the human brain develops during the earliest stages of life.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Infants born at the John Radcliffe Hospital, Oxford

Infants born at or after 35+0 weeks gestation

Infants with a postnatal age of <7 days

Infants for whom parents/legal guardians have given written informed consent for participation.

Disqualifiers

Hypoxic Ischaemic Encephalopathy (HIE)

Intraventricular haemorrhage (IVH) > grade II

Received any analgesics or sedatives in the last 24 hours

Congenital malformation or genetic condition known to affect neurological development

Trial population

Participants in this study will be infants born at the John Radcliffe Hospital, Oxford at or after 35+0 weeks gestation with a postnatal age of \<7 days.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

FMRI connectivity

Differences in functional connectivity of spontaneous fMRI brain activity

Time frame
Two years

Secondary outcomes

1

Changes in fMRI connectivity

Longitudinal changes in fMRI connectivity over the entire duration of the study

Time frame
Two years

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: