Meningioma and Embolism Thrombosis Risk & Investigation of Coagulation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital Tuebingen
About this trial
Despite being generally benign tumors, meningiomas are associated with an increased risk for thrombembolic complications after surgical resection. The molecular mechanisms underlying this circumstance are still unknown.
In this prospective observational trial, the investigators aim to evaluate the changes in coagulation and platelet function caused by tumor resection.
Blood samples are obtained by patients undergoing meningioma resection before and immediately after resection to detect said changes.
As a control cohort, blood samples are obtained from patients undergoing resection for glioma.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients undergoing resection for meningioma or
Patients undergoing resection for glioma or
Healthy controls
written consent for study participation
Disqualifiers
None
Trial population
Patients with intracranial tumors 1. meningeoma 2. glioma (control)
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
100 Participants
are grouped into 3 trial groupsGroup A: Meningioma resection
Group B: Glioma resection
Group C: Healthy controls
Trial outcomes
Primary outcomes
1
Tissue factor
Concentration of tissue factor at pre-surgery and immediately after tumor resection (during close-up).
Time frame
duration of surfical tumor resection (a few hours)Sponsors and contacts
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Source ClinicalTrials.gov