About this trial
This study examines how different phases of the menstrual cycle are associated with selected performance and musculoskeletal parameters in physically active women aged 18-35 years.
Participants will track their menstrual cycle using a mobile app for approximately 2 months and attend 3 laboratory visits scheduled to specific cycle phases.
At each visit, participants will complete non-invasive assessments including lower-limb strength/performance testing, musculoskeletal measurements (muscle and tendon properties), body composition assessment, and symptom-related questionnaires.
The goal is to improve understanding of physiological variability across the menstrual cycle and support evidence-based planning of training, testing, and clinical practice in women.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Female, age 18-35 years
Disqualifiers
Irregular menstrual cycle (outside protocol-defined regularity)
Trial population
Premenopausal women aged 18-35 years from the general population with occasional to recreational physical activity, recruited for repeated within-subject assessments across predefined menstrual cycle phases.
Trial design
Cohort
Prospective
Treatments tested in this trial
Menstrual Cycle Tracking
Other interventionMenstrual cycle monitoring using a mobile application for approximately 2 months to schedule laboratory visits to predefined cycle phases.
Performance and Strength Testing
Other interventionRepeated lower-limb performance/strength assessments during laboratory visits in different menstrual cycle phases.
Musculoskeletal Assessment
Other interventionNon-invasive assessment of selected muscle and tendon mechanical properties across cycle phases.
Body Composition and Symptom Assessment
Other interventionBody composition measurement and collection of self-reported menstrual-related symptoms at laboratory visits.
Treatment groups
Trial outcomes
Primary outcomes
Phase-specific change in lower-limb neuromuscular performance across the menstrual cycle
Within-subject differences in lower-limb performance/strength outcomes measured during three laboratory visits scheduled to predefined menstrual cycle phases.
Secondary outcomes
Phase-specific differences in muscle mechanical properties
Within-subject changes in selected skeletal muscle mechanical properties measured non-invasively across predefined menstrual cycle phases.
Phase-specific differences in tendon mechanical properties
Within-subject changes in selected tendon mechanical properties measured non-invasively across predefined menstrual cycle phases.
Phase-specific differences in body composition variables
Within-subject differences in body composition parameters assessed at laboratory visits scheduled to predefined menstrual cycle phases.
Menstrual-related symptom profile across menstrual cycle phases
Self-reported menstrual-related symptoms recorded via questionnaires/standardized symptom reporting and compared across predefined cycle phases.
Sponsors and contacts
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