Mental Health and Suicidality in Glioblastoma Patients in Germany
ConditionGlioblastoma (GBM)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Essen
About this trial
The aim of the study is to use standardized questionnaires to systematically record influencing factors or predictors for suicidal behavior in glioblastoma patients, particularly with regard to existing depression and anxiety symptoms.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Newly diagnosed glioblastoma, IDH wild-type (CNS WHO classification of 2021) after finishing radiotherapy (before first recurrence)
Age ≥ 18 years
Disqualifiers
Participants with clinically significant aphasia or language barrier as assessed by the investigator
History of other malignant tumors
Known tumor predisposition syndrome (e.g., Li-Fraumeni syndrome, Cowden syndrome, etc.)
Recurrent glioblastoma
Trial population
glioblastoma patients
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Medical history, physical examination, completing questionnaires, data collection
Diagnostic testMedical history Physical examination Completion of validated questionnaires: * Suicide Scale (SSEV) * Patient Health Questionnaire-8 (PHQ-8) * Generalized Anxiety Disorder-7 (GAD-7) * EORTC-QLQ-30 * EORTC-QLQ-BN-20 * Short questionnaire on social support for chronic illnesses (SUCE-4) Data collection from medical records
Treatment groups
180 Participants
are divided into 1 treatment groupGroup A: glioblastoma patients1 intervention
Trial outcomes
Primary outcomes
1
Suicidality
Measured using a questionnaire
Time frame
in the last 4 weeks before participating in the studySecondary outcomes
1
Depression
Measured using a questionnaire
Time frame
in the last 2 weeks before participating in the study2
Anxiety
Measured using a questionnaire
Time frame
in the last 2 weeks before participating in the study3
Health-related quality of life (HRQoL)
Measured using a questionnaire
Time frame
in the last week before participating in the study4
Social support
Measured using a questionnaire
Time frame
at the time of participation in the study (current status queried)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
University Hospital, Essen
Lead sponsor
University Hospital Muenster
Collaborator
Charite University, Berlin, Germany
Collaborator
University Hospital Heidelberg
Collaborator
Neurological Clinic, Knappschaftskrankenhaus Bochum-Langendreer, Bochum, Germany
Collaborator
Universitätsklinikum Hamburg-Eppendorf
Collaborator
Source ClinicalTrials.gov