Mentalization and Social Cognition in Adolescents After Suicide Attempt
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-16
SponsorAssistance Publique - Hôpitaux de Paris
About this trial
This study investigates the risk of violent suicide attempts in adolescents, with a particular focus on social cognition and sleep disturbances, to better understand the cognitive and behavioral mechanisms involved and to inform more targeted prevention strategies.
Violent suicide attempts are defined as the use of methods with a high immediate lethal potential. They are associated with distinct clinical profiles and specific risk factors, including an increased risk of recurrence and completed suicide.
Although the association between suicidal behavior and psychiatric disorders is well established, evidence regarding the underlying neurocognitive factors remains inconsistent. In particular, little is known about the role of social cognition in suicidal risk among adolescents. Research in this area is limited, leaving an important gap in our understanding of the cognitive processes that may contribute to the emergence of suicidal thoughts and behaviors during adolescence.
In addition, studies conducted in community-based adolescent cohorts have shown that insufficient sleep duration is independently associated with increased suicidal ideation and suicidal behavior, even after accounting for depressive symptoms.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adolescents aged 12 to 16 years, inclusive
Having made a violent or non-violent suicide attempt
Hospitalized in the Department of Child and Adolescent Psychiatry at Necker Children's Hospital
No intellectual disability (IQ > 70)
Disqualifiers
Current psychotic disorder or documented history of a psychotic disorder
Current manic or hypomanic episode
Severe neurological or medical condition likely to significantly affect cognitive performance
Moderate-to-severe substance use disorder requiring specialized treatment
Trial design
Design model
Parallel
Treatments tested in this trial
Test
Other interventionClinical Assessment of Social Cognition, including : * PERSO: measurement of social reasoning, through the analysis and interpretation of social situations, the understanding of the emotions and intentions of others, as well as the adaptation of responses to the relational context; * Movie for the Assessment of Social Cognition (MASC): video task measuring understanding of the mental states, intentions and emotions of others (theory of mind), * Ambiguous Intentions Hostility Questionnaire (AIHQ): measurement of attribution biases and hostile interpretations in social interactions.
Questionnaires
Other interventionTo explore the associations between performance on the most discriminative social cognition measures (derived from the Clinical Assessment of Social Cognition \[ClaCoS\] battery) and several secondary variables that may influence socio-cognitive functioning or the characteristics of the suicide attempt, including: * Suicidal intent, assessed using the Suicide Intent Scale (SIS) * Anxiety symptoms, assessed using the Screen for Child Anxiety Related Emotional Disorders (SCARED) * Depressive symptoms, assessed using the Major Depressive Disorder (MDD) module of the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) * Socioeconomic vulnerability, assessed using the EPICES deprivation score * Attachment styles, assessed using the Adolescent Relationship Scale Questionnaire (ARSQ) * Sleep characteristics, assessed using the Sleep Disturbance Scale for Children (SDSC) and the Disturbing Dreams and Nightmare Severity Index (DDNSI) * Everyday social cognition skills, assessed us
Treatment groups
82 Participants
are divided into 2 treatment groupsGroup A: Adolescents who have attempted violent suicideExperimental treatment 2 interventions
Group B: Adolescents who have attempted nonviolent suicideExperimental treatment 2 interventions
Trial outcomes
Primary outcomes
1
Level of performance in social cognition in the two groups of adolescents hospitalized following a suicide attempt, distinguishing: adolescents who made a violent suicide attempt and those who made a non-violent suicide attempt
Social cognition will be assessed using three subtests from the Clinical Assessment of Social Cognition (ClaCoS) battery. The PERSO task evaluates social reasoning through the interpretation of social situations and yields a total score based on the number of correct responses. The MASC (Movie for the Assessment of Social Cognition) assesses theory of mind using a video-based task and provides a total score corresponding to the number of correctly inferred mental states. The AIHQ assesses attributional biases in ambiguous social situations and generates scores reflecting hostile and intentionality attribution biases. For all three measures, scores will be analysed as continuous variables, with higher scores indicating better social cognitive performance (PERSO, MASC) or stronger attributional biases (AIHQ).
Time frame
1 daySecondary outcomes
1
Severity of suicidal intention
Measurement of the severity of suicidal intention by the Suicide Intent Scale (SIS) rated by the service psychologist based on information collected in the clinical file in the two groups of adolescents hospitalized following a suicide attempt, distinguishing: adolescents who made a violent suicide attempt and those who made a non-violent suicide attempt.
Time frame
1 day2
Level of socio-economic precariousness
Level of precariousness and social vulnerability score using the EPICES questionnaire in the two groups of adolescents hospitalized following a suicide attempt, distinguishing: adolescents who made a violent suicide attempt and those who made a non-violent suicide attempt.
Time frame
1 day3
Level of anxiety
Level of anxiety assessed using the Screen for Child Anxiety Related Emotional Disorders (SCARED), a self-report questionnaire measuring specific and generalized anxiety symptoms in the two groups of adolescents hospitalized following a suicide attempt, distinguishing: adolescents who made a violent suicide attempt and those who made a non-violent suicide attempt.
Time frame
1 day4
Level of depressive disorder
Assessment of depression by the Major Depressive Disorder (MDD) section of the K-SADS (Kiddie Schedule for Affective Disorders and Schizophrenia), a semi-structured interview tool used to diagnose a major depressive episode according to the Diagnostic and Statistical Manual of Mental Disorders criteria in the two groups of adolescents hospitalized following a suicide attempt, distinguishing: adolescents who made a violent suicide attempt and those who made a non-violent suicide attempt.
Time frame
1 daySponsors and contacts
Click on the lead sponsor to view all of their trials.
Assistance Publique - Hôpitaux de Paris
Lead sponsor
URC-CIC Paris Descartes Necker Cochin
Collaborator
Source ClinicalTrials.gov
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