Health TrialsbyHealthPanel

Metastatic Pathologic Fractures, Short Term Results

ConditionsPathologic FractureBone MetastasesMetastatic Cancer
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorAnkara University

About this trial

This is a single center prospective study to compare the short term results of prosthesis, nail and plate-screw surgeries for metastatic pathologic fractures.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

metastatic pathologic fracture

operated via endoprosthesis, intramedullary nail or plate & screws

Disqualifiers

primary bone tumor

conservative management

neuromuscular disease

periprosthetic fractures

Trial population

Study population includes patients with metastatic pathologic fractures treated via endoprosthesis, intramedullay nail or plate \& screws.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • endoprosthetic reconstruction

    Procedure/Surgery

    This is a type of surgery in which the affected part of the bone and joint is removed, and replaced by a prosthesis.

  • Intramedullary nailing

    Procedure/Surgery

    This is a type of surgery in which the affected bone is stabilized by a nail. The affected part could be removed or retained. If removed, the defect is filled with bone cement.

  • Open reduction internal fixation with plate and screws

    Procedure/Surgery

    This is a type of surgery in which the affected part of the bone is visualized completely, after the reduction is achieved, the fixation is provided with appropriate plates and screws. Again the affected part could be removed or retained. If removed, the defect is filled with bone cement.

Treatment groups

200 Participants
are divided into 3 treatment groups
Group A: endoprosthetic reconstruction1 intervention
Group B: intramedullary nail1 intervention
Group C: open reduction internal fixation with plate and screws1 intervention

Trial outcomes

Primary outcomes

1

Musculoskeletal Tumor Society (MSTS) score

MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.

Time frame
Preoperative
2

Musculoskeletal Tumor Society (MSTS) score

MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.

Time frame
Postoperative 1st day
3

Musculoskeletal Tumor Society (MSTS) score

MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.

Time frame
Postoperative 1st week
4

Musculoskeletal Tumor Society (MSTS) score

MSTS score is for evaluating the patients with bone tumors. It consists of six domains; scored on a 0 to 5 scale and transformed into an overall score ranging from 0 to 100% with a higher score indicating better function.

Time frame
Postoperative 1st month

Secondary outcomes

1

Days at hospital after surgery

Hospitalization length required after the surgery.

Time frame
up to 1 month
2

Survival

Time that the patient lives after the surgery

Time frame
up to 3 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ankara University

Lead sponsor

Source ClinicalTrials.gov
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