Micro-nanoplastic Exposure and Coronary Microcirculatory Dysfunction as Well as Cardiovascular Outcomes
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBeijing Anzhen Hospital
About this trial
With strict quality control procedures applied throughout microplastic testing, this study will assess the association between baseline circulating micro-nanoplastic exposure and coronary microvascular dysfunction, as well as subsequent long-term cardiovascular outcomes.
Eligibility criteria
Qualifiers
Age ≥ 18;
Patients with clinical indications for undergoing invasive coronary angiography and coronary functional assessment (including fractional flow reserve [FFR], CFR, and IMR);
Voluntarily sign the written informed consent form.
Disqualifiers
The surgeon (or attending physician) determines that the patient is not suitable for or cannot tolerate a coronary physiological examination;
Intraoperative coronary angiography reveals a stenosis of>90% in any non-left main coronary artery lumen or a stenosis of>50% in the left main coronary artery lumen;
Left ventricular ejection fraction <35% or cardiogenic shock or cardiac arrest;
Previous history of invasive procedures/treatments;
Trial design
Treatments tested in this trial
- micro-nanoplastic examination
- Microvascular Function Examination
Treatment groups
184 Participants
are divided into 1 treatment groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov